Parathyroid hormone update

被引：23

作者：

Hamann, Kendal L.

Lane, Nancy E.

机构：

[1] Univ Calif Davis, Med Ctr, Div Endocrinol, Sacramento, CA 95817 USA

[2] Sacramento Mather Vet Affairs Med Ctr, Mather, CA 95655 USA

[3] Univ Calif Davis, Med Ctr, Dept Internal Med, Sacramento, CA 95817 USA

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2006年 / 32卷 / 04期

关键词：

D O I：

10.1016/j.rdc.2006.07.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Osteoporosis afflicts an estimated 10 million United States citizens, and approximately one in two women and one in four men who are older than the age of 50 will suffer from an osteoporosis-related fracture in their remaining lifetimes. US Food and Drug Administration (FDA)-approved therapies for the treatment and prevention of osteoporosis include calcium and vitamin D supplements and antiresorptive therapies. Recombinant human parathyroid hormone (rhPTH) and recombinant bioactive fragments of human parathyroid hormone (PTH) are emerging as a unique new class of treatment options for osteoporosis. This article briefly reviews the physiology and rationale for the use of PTH for the treatment of osteoporosis, and provides a more detailed update on the application of recent clinical trials of PTH to clinical practice.

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收藏

页码：703 / +

页数：19

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