Sulfonyl chloride formation from thiol derivatives by N-chlorosuccinimide mediated oxidation

被引：86

作者：

Nishiguchi, Atsuko ^{[1
]}

Maeda, Kazuhiro ^{[1
]}

Miki, Shokyo ^{[1
]}

机构：

[1] Takeda Pharmaceut Co Ltd, Chem Dev Labs, Yodogawa Ku, Osaka 5328686, Japan

来源：

SYNTHESIS-STUTTGART | 2006年 / 24期

关键词：

thiol derivatives; oxidation; solvent effects; NCS; chlorosulfonation;

D O I：

10.1055/s-2006-950353

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oxidation of several thiol derivatives by a combination of N-chlorosuccinimide and dilute hydrochloric acid proceeded smoothly, affording the corresponding sulfonyl chlorides in good yield.

引用

页码：4131 / 4134

页数：4

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