Bioconjugated silicon quantum dots from one-step green synthesis

被引：75

作者：

Intartaglia, Romuald ^{[1
]}

Barchanski, Annette ^{[2
]}

Bagga, Komal ^{[1
]}

Genovese, Alessandro ^{[3
]}

Das, Gobind ^{[5
]}

Wagener, Philipp ^{[4
]}

Di Fabrizio, Enzo ^{[5
]}

Diaspro, Alberto ^{[1
]}

Brandi, Fernando ^{[1
]}

Barcikowski, Stephan ^{[4
]}

机构：

[1] Ist Italiano Tecnol, Dept Nanophys, I-16163 Genoa, Italy

[2] Laser Zentrum Hannover eV, Nanotechnol Dept, D-30419 Hannover, Germany

[3] Ist Italiano Tecnol, Dept Nanochem, I-16163 Genoa, Italy

[4] Univ Duisburg Essen, Ctr Nanointegrat Duisburg Essen CeNIDE, D-45141 Essen, Germany

[5] Ist Italiano Tecnol, Dept Nanostruct, I-16163 Genoa, Italy

来源：

NANOSCALE | 2012年 / 4卷 / 04期

关键词：

IN-SITU BIOCONJUGATION; PULSED-LASER-ABLATION; GOLD NANOPARTICLES; ROOM-TEMPERATURE; NANOCRYSTALS; FUNCTIONALIZATION; PHOTOSENSITIZERS; OXYGEN;

D O I：

10.1039/c2nr11763k

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Biofunctionalized silicon quantum dots were prepared through a one step strategy avoiding the use of chemical precursors. UV-Vis spectroscopy, Raman spectroscopy and HAADF-STEM prove oligonucleotide conjugation to the surface of silicon nanoparticle with an average size of 4 nm. The nanoparticle size results from the size-quenching effect during in situ conjugation. Photoemissive properties, conjugation efficiency and stability of these pure colloids were studied and demonstrate the bio-application potential, e. g. for nucleic acid vector delivery with semiconducting, biocompatible nanoparticles.

引用

页码：1271 / 1274

页数：4

共 47 条

[1]

Silicon Nanocrystals Produced by Nanosecond Laser Ablation in an Organic Liquid [J].

Abderrafi, Kamal ;

Garcia Calzada, Raul ;

Gongalsky, Maxim B. ;

Suarez, Isaac ;

Abarques, Rafael ;

Chirvony, Vladimir S. ;

Timoshenko, Victor Yu ;

Ibanez, Rafael ;

Martinez-Pastor, Juan P. .

JOURNAL OF PHYSICAL CHEMISTRY C, 2011, 115 (12) :5147-5151

[2]

Laser ablation synthesis in solution and size manipulation of noble metal nanoparticles [J].

Amendola, Vincenzo ;

Meneghetti, Moreno .

PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2009, 11 (20) :3805-3821

[3]

[Anonymous], RECENT ADV LASER PRO

[4]

Silicon Nanoparticles as Hyperpolarized Magnetic Resonance Imaging Agents [J].

Aptekar, Jacob W. ;

Cassidy, Maja C. ;

Johnson, Alexander C. ;

Barton, Robert A. ;

Lee, Menyoung ;

Ogier, Alexander C. ;

Vo, Chinh ;

Anahtar, Melis N. ;

Ren, Yin ;

Bhatia, Sangeeta N. ;

Ramanathan, Chandrasekhar ;

Cory, David G. ;

Hill, Alison L. ;

Mair, Ross W. ;

Rosen, Matthew S. ;

Walsworth, Ronald L. ;

Marcus, Charles M. .

ACS NANO, 2009, 3 (12) :4003-4008

[5]

Design of Bi-functional Bioconjugated Gold Nanoparticles by Pulsed Laser Ablation with Minimized Degradation [J].

Barchanski, Annette ;

Sajti, Csaba Laszlo ;

Sehring, Camilla ;

Petersen, Svea ;

Barcikowski, Stephan .

JOURNAL OF LASER MICRO NANOENGINEERING, 2011, 6 (02) :124-130

[6]

Observation of a magic discrete family of ultrabright Si nanoparticles [J].

Belomoin, G ;

Therrien, J ;

Smith, A ;

Rao, S ;

Twesten, R ;

Chaieb, S ;

Nayfeh, MH ;

Wagner, L ;

Mitas, L .

APPLIED PHYSICS LETTERS, 2002, 80 (05) :841-843

[7]

Ultrafast laser based "green" synthesis of non-toxic nanoparticles in aqueous solutions [J].

Besner, S. ;

Kabashin, A. V. ;

Winnik, F. M. ;

Meunier, M. .

APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING, 2008, 93 (04) :955-959

[8]

Borsella E., 2010, SILICON NANOCRYSTALS

[9]

Chan W. C. W., 2007, LANDES BIOSCIENCE SP

[10]

Synthesis of gold colloids by laser ablation in thiol-alkane solutions [J].

Compagnini, G ;

Scalisi, AA ;

Puglisi, O ;

Spinella, C .

JOURNAL OF MATERIALS RESEARCH, 2004, 19 (10) :2795-2798

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