Synthesis of 13-ethyl-17-hydroxy-11-methylene-18, 19-dinor-17 alpha-pregn-4-en-20-yn-3-one (3-oxo desogestrel)

被引：7

作者：

Gao, HW ^{[1
]}

Su, XD ^{[1
]}

Li, ZS ^{[1
]}

机构：

[1] BEIJING MED UNIV,SCH PHARMACEUT SCI,BEIJING 100083,PEOPLES R CHINA

来源：

STEROIDS | 1997年 / 62卷 / 05期

关键词：

3-keto-desogestrel; synthesis; hydroboration/alkaline hydrogen peroxide oxidation;

D O I：

10.1016/S0039-128X(97)00006-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A synthesis of the steroid hormone, 3-keto-desogestrel (1), with the total yield of 10% starting from d-13-beta-ethyl-3-methoxy-gona-1,3,5(10),8-tetraen-17-beta-ol (3) is described.

引用

页码：398 / 402

页数：5

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