MINER: software for phylogenetic motif identification

被引：20

作者：

La, D

Livesay, DR ^{[1
]}

机构：

[1] Calif State Polytech Univ Pomona, Dept Chem, Pomona, CA 91767 USA

[2] Calif State Polytech Univ Pomona, Dept Biol Sci, Pomona, CA 91767 USA

[3] Calif State Polytech Univ Pomona, Ctr Macromol Modeling & Mat Design, Pomona, CA 91767 USA

来源：

NUCLEIC ACIDS RESEARCH | 2005年 / 33卷

关键词：

D O I：

10.1093/nar/gki465

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

MINER is web-based software for phylogenetic motif ( PM) identification. PMs are sequence regions (fragments) that conserve the overall familial phylogeny. PMs have been shown to correspond to a wide variety of catalytic regions, substrate- binding sites and protein interfaces, making them ideal functional site predictions. The MINER output provides an intuitive interface for interactive PM sequence analysis and structural visualization. The web implementation of MINER is freely available at http://www.pmap. csupomona.edu/MINER/. Source code is available to the academic community on request.

引用

页码：W267 / W270

页数：4

共 13 条

[1] ConSurf: An algorithmic tool for the identification of functional regions in proteins by surface mapping of phylogenetic information [J].