Neuronal migration in the adult brain: are we there yet?

被引:154
作者
Ghashghaei, H. Troy
Lai, Cary
Anton, E. S.
机构
[1] Univ N Carolina, Sch Med, Ctr Neurosci, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Sch Med, Dept Cell & Cell Physiol, Chapel Hill, NC 27599 USA
[3] N Carolina State Univ, Sch Vet Med, Dept Mol Biomed Sci, Raleigh, NC 27606 USA
[4] Scripps Res Inst, Mol & Integrat Neurosci Dept, La Jolla, CA 92037 USA
关键词
D O I
10.1038/nrn2074
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The generation and targeting of appropriate numbers and types of neurons to where they are needed in the brain is essential for the establishment, maintenance and modification of neural circuitry. This review aims to summarize the patterns, mechanisms and functional significance of neuronal migration in the postnatal brain, with an emphasis on the migratory events that persist in the mature brain.
引用
收藏
页码:141 / 151
页数:11
相关论文
共 172 条
[1]   Potential role for adult neurogenesis in the encoding of time in new memories [J].
Aimone, James B. ;
Wiles, Janet ;
Gage, Fred H. .
NATURE NEUROSCIENCE, 2006, 9 (06) :723-727
[3]   Interneuron migration from basal forebrain to neocortex: Dependence on Dlx genes [J].
Anderson, SA ;
Eisenstat, DD ;
Shi, L ;
Rubenstein, JLR .
SCIENCE, 1997, 278 (5337) :474-476
[4]   Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain [J].
Andrews, William ;
Liapi, Anastasia ;
Plachez, Celine ;
Camurri, Laura ;
Zhang, Jiangyang ;
Mori, Susumu ;
Murakami, Fujio ;
Parnavelas, John G. ;
Sundaresan, Vasi ;
Richards, Linda J. .
DEVELOPMENT, 2006, 133 (11) :2243-2252
[5]   Receptor tyrosine kinase ErbB4 modulates neuroblast migration and placement in the adult forebrain [J].
Anton, ES ;
Ghashghaei, HT ;
Weber, JL ;
McCann, C ;
Fischer, TM ;
Cheung, ID ;
Gassmann, M ;
Messing, A ;
Klein, R ;
Schwab, MH ;
Lloyd, KCK ;
Lai, C .
NATURE NEUROSCIENCE, 2004, 7 (12) :1319-1328
[6]  
BAYER SA, 1983, EXP BRAIN RES, V50, P329
[7]   Evidence of newly generated neurons in the human olfactory bulb [J].
Bédard, A ;
Parent, A .
DEVELOPMENTAL BRAIN RESEARCH, 2004, 151 (1-2) :159-168
[8]   Neocortical neurogenesis in humans is restricted to development [J].
Bhardwaj, Ratan D. ;
Curtis, Maurice A. ;
Spalding, Kirsty L. ;
Buchholz, Bruce A. ;
Fink, David ;
Bjork-Eriksson, Thomas ;
Nordborg, Claes ;
Gage, Fred H. ;
Druid, Henrik ;
Eriksson, Peter S. ;
Frisen, Jonas .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (33) :12564-12568
[9]   GABA release and uptake regulate neuronal precursor migration in the postnatal subventricular zone [J].
Bolteus, AJ ;
Bordey, A .
JOURNAL OF NEUROSCIENCE, 2004, 24 (35) :7623-7631
[10]   The first neurons of the human cerebral cortex [J].
Bystron, Irina ;
Rakic, Pasko ;
Molnar, Zoltan ;
Blakemore, Colin .
NATURE NEUROSCIENCE, 2006, 9 (07) :880-886