A review of biological factors implicated in abdominal aortic aneurysm rupture

被引:220
作者
Choke, E
Cockerill, G
Wilson, WRW
Sayed, S
Dawson, J
Loftus, I
Thompson, MM
机构
[1] Univ London St Georges Hosp, Dept Vasc Surg, Sch Med, London SW17 0QT, England
[2] Leicester Royal Infirm, Dept Vasc Surg, Leicester, Leics, England
关键词
abdominal aortic aneurysm; rupture; matrix metalloproteinase; enzyme; collagen;
D O I
10.1016/j.ejvs.2005.03.009
中图分类号
R61 [外科手术学];
学科分类号
摘要
Abdominal aortic aneurysm (AAA) rupture is the 13th commonest cause of death in the Western World. Although considerable research has been applied to the aetiology and mechanism of aneurysm expansion, little is known about the mechanism of rupture. Aneurysm rupture was historically considered to be a simple physical process that occurred when the aortic wall could no longer contain the haemodynamic stress of the circulation. However, AAAs do not conform to the law of Laplace and there is growing evidence that aneurysm rupture involves a complex series of biological changes in the aortic wall. This paper reviews the available data on patient variables associated with aneurysm rupture and presents the evidence implicating biological factors in AAA rupture.
引用
收藏
页码:227 / 244
页数:18
相关论文
共 191 条
[21]   HYPOXIC INJURY TO HUMAN ALVEOLAR MACROPHAGES ACCELERATES RELEASE OF PREVIOUSLY BOUND NEUTROPHIL ELASTASE - IMPLICATIONS FOR LUNG CONNECTIVE-TISSUE INJURY INCLUDING PULMONARY-EMPHYSEMA [J].
CAMPBELL, EJ ;
WALD, MS .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1983, 127 (05) :631-635
[22]  
CHOYKE PL, 1993, LANCET, V342, P1377
[23]   TRANSMURAL ORGANIZATION OF THE ARTERIAL MEDIA - THE LAMELLAR UNIT REVISITED [J].
CLARK, JM ;
GLAGOV, S .
ARTERIOSCLEROSIS, 1985, 5 (01) :19-34
[24]   AORTIC COLLAGENASE ACTIVITY AS AFFECTED BY LAPAROTOMY, CECAL RESECTION, AORTIC MOBILIZATION, AND AORTOTOMY IN RATS [J].
COHEN, JR ;
PERRY, MO ;
HARIRI, R ;
HOLT, J ;
ALVAREZ, O .
JOURNAL OF VASCULAR SURGERY, 1984, 1 (04) :562-565
[25]   Chondrocyte matrix metalloproteinase-8 - Human articular chondrocytes express neutrophil collagenase [J].
Cole, AA ;
Chubinskaya, S ;
Schumacher, B ;
Huch, K ;
CsSzabo, G ;
Yao, J ;
Mikecz, K ;
Hasty, KA ;
Kuettner, KE .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (18) :11023-11026
[26]   Transient exposure to elastase induces mouse aortic wall smooth muscle cell production of MCP-1 and RANTES during development of experimental aortic aneurysm [J].
Colonnello, JS ;
Hance, KA ;
Shames, ML ;
Wyble, CW ;
Ziporin, SJ ;
Leidenfrost, JE ;
Ennis, TL ;
Upchurch, GR ;
Thompson, RW .
JOURNAL OF VASCULAR SURGERY, 2003, 38 (01) :138-146
[27]   IN-SITU ISCHEMIA AND HYPOXIA ENHANCE ALVEOLAR MACROPHAGE TISSUE FACTOR EXPRESSION [J].
COMPEAU, CG ;
MA, J ;
DECAMPOS, KN ;
WADDELL, TK ;
BRISSEAU, GF ;
SLUTSKY, AS ;
ROTSTEIN, OD .
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1994, 11 (04) :446-455
[28]   VARIABLES THAT AFFECT THE EXPANSION RATE AND OUTCOME OF SMALL ABDOMINAL AORTIC-ANEURYSMS [J].
CRONENWETT, JL ;
SARGENT, SK ;
WALL, MH ;
HAWKES, ML ;
FREEMAN, DH ;
DAIN, BJ ;
CURE, JK ;
WALSH, DB ;
ZWOLAK, RM ;
MCDANIEL, MD ;
SCHNEIDER, JR .
JOURNAL OF VASCULAR SURGERY, 1990, 11 (02) :260-269
[29]   Variables that affect the expansion rate and rupture of abdominal aortic aneurysms [J].
Cronenwett, JL .
ABDOMINAL AORTIC ANEURYSM: GENETICS, PATHOPHYSIOLOGY, AND MOLECULAR BIOLOGY, 1996, 800 :56-67
[30]  
CRONENWETT JL, 1985, SURGERY, V98, P472