Decrease in the relative heterogeneity of health with age: A cross-national comparison

被引:17
作者
Mitnitski, A [1 ]
Rockwood, K [1 ]
机构
[1] Dalhousie Univ, Div Geriatr Med, Dept Med, Halifax, NS B3H 1C6, Canada
关键词
ageing; frailty (deficits accumulation) index; relative heterogeneity;
D O I
10.1016/j.mad.2005.09.007
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Using data from seven studies from Canada, Australia and the United States we were able to evaluate the heterogeneity of health status for 34,095 people aged 60 years and older. We found that relative heterogeneity (measured by the coefficient of variation) decreased with age. The coefficient of variation also decreased as a function of deficit accumulation (i.e. was lower when people demonstrated more deficits) displaying a power-law relationship. The exponent was close to 0.5, and therefore belongs to the dynamic universality class, which is typical for complex dynamical networks. We interpret this as showing that decline in relative heterogeneity is a robust finding, and represents, at the group level, increased vulnerability amongst elderly people. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:70 / 72
页数:3
相关论文
共 19 条
[1]  
ASHBY WR, 1952, INTRO CYBERNETICS, P295
[2]   Separating internal and external dynamics of complex systems -: art. no. 068701 [J].
de Menezes, MA ;
Barabási, AL .
PHYSICAL REVIEW LETTERS, 2004, 93 (06) :068701-1
[3]   Fluctuations in network dynamics -: art. no. 028701 [J].
de Menezes, MA ;
Barabási, AL .
PHYSICAL REVIEW LETTERS, 2004, 92 (02) :4
[4]   Frailty index as a measure of biological age in a Chinese population [J].
Goggins, WB ;
Woo, J ;
Sham, A ;
Ho, SC .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2005, 60 (08) :1046-1051
[5]   Standardization of the diagnosis of dementia in the Canadian Study of Health and Aging [J].
Graham, JE ;
Rockwood, K ;
Beattie, BL ;
McDowell, I ;
Eastwood, R ;
Gauthier, S .
NEUROEPIDEMIOLOGY, 1996, 15 (05) :246-256
[6]   SELF-RATED HEALTH AND MORTALITY IN THE NHANES-I EPIDEMIOLOGIC FOLLOW-UP-STUDY [J].
IDLER, EL ;
ANGEL, RJ .
AMERICAN JOURNAL OF PUBLIC HEALTH, 1990, 80 (04) :446-452
[7]   Do cognitive complaints either predict future cognitive decline or reflect past cognitive decline? A longitudinal study of an elderly community sample [J].
Jorm, AF ;
Christensen, H ;
Korten, AE ;
Henderson, AS ;
Jacomb, PA ;
Mackinnon, A .
PSYCHOLOGICAL MEDICINE, 1997, 27 (01) :91-98
[8]   Why do we age? [J].
Kirkwood, TBL ;
Austad, SN .
NATURE, 2000, 408 (6809) :233-238
[9]   Network theory of aging [J].
Kirkwood, TBL ;
Kowald, A .
EXPERIMENTAL GERONTOLOGY, 1997, 32 (4-5) :395-399
[10]  
MANTON KG, 1988, J GERONTOL SOC SCI, V43