Magnesium as a biodegradable and bioabsorbable material for medical implants

被引:251
作者
Brar, Harpreet S. [1 ]
Platt, Manu O. [2 ]
Sarntinoranont, Malisa [3 ]
Martin, Peter I. [1 ]
Manuel, Michele V. [1 ]
机构
[1] Univ Florida, Dept Mat Sci & Engn, Gainesville, FL 32611 USA
[2] Georgia Tech & Emory Univ, Wallace H Coulter Dept Biomed Engn, Atlanta, GA USA
[3] Univ Florida, Dept Mech & Aerosp Engn, Gainesville, FL 32611 USA
关键词
CORROSION BEHAVIOR; ABSORBABLE METAL; ALLOYS; ADHESION; MECHANISMS;
D O I
10.1007/s11837-009-0129-0
中图分类号
T [工业技术];
学科分类号
120111 [工业工程];
摘要
For many years, stainless steel, cobalt-chromium, and titanium alloys have been the primary biomaterials used for load-bearing applications. However, as the need for structural materials in temporary implant applications has grown, materials that provide short-term structural support and can be reabsorbed into the body after healing are being sought. Since traditional metallic biomaterials are typically biocompatible but not biodegradable, the potential for magnesium-based alloys in biomedical applications has gained more interest. This paper summarizes the history and current status of magnesium as a bioabsorbable implant material. Also discussed is the development of a magnesium-zinc-calcium alloy that demonstrates promising degradation behavior.
引用
收藏
页码:31 / 34
页数:4
相关论文
共 38 条
[1]
[Anonymous], 1992, SMITHELLS METALS REF
[2]
[Anonymous], WILEY SERIES SCI TEC
[3]
Black J., 1988, Orthopaedic biomaterials in research and practice
[4]
OSTEOLYTIC CHANGES ACCOMPANYING DEGRADATION OF ABSORBABLE FRACTURE FIXATION IMPLANTS [J].
BOSTMAN, OM .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 1991, 73 (04) :679-682
[6]
ELIN RJ, 1987, CLIN CHEM, V33, P1965
[7]
PHYSICOMECHANICAL PROPERTIES OF DEGRADABLE POLYMERS USED IN MEDICAL APPLICATIONS - A COMPARATIVE-STUDY [J].
ENGELBERG, I ;
KOHN, J .
BIOMATERIALS, 1991, 12 (03) :292-304
[8]
Hamid Huda, 2007, Mcgill J Med, V10, P105
[9]
HELLER J, 1990, BIODEGRADABLE POLYM, P121
[10]
Biocorrosion of magnesium alloys: a new principle in cardiovascular implant technology? [J].
Heublein, B ;
Rohde, R ;
Kaese, V ;
Niemeyer, M ;
Hartung, W ;
Haverich, A .
HEART, 2003, 89 (06) :651-656