The role of biomethylation in toxicity and carcinogenicity of arsenic:: A research update

被引:318
作者
Styblo, M
Drobná, Z
Jaspers, I
Lin, S
Thomas, DJ
机构
[1] Univ N Carolina, Dept Pediat, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Dept Nutr, Chapel Hill, NC 27599 USA
[3] Univ N Carolina, Ctr Environm Med & Lung Biol, Chapel Hill, NC 27599 USA
[4] Univ N Carolina, Curriculum Toxicol, Chapel Hill, NC 27599 USA
[5] US EPA, Pharmacokinet Branch, Expt Toxicol Div, Natl Hlth & Environm Effects Res Lab,Off Res & De, Res Triangle Pk, NC 27711 USA
关键词
AP-1; arsenic; cancer; inhibition; methylated arsenic; methylation; methyltransferase; toxicity; transcription control;
D O I
10.1289/ehp.02110s5767
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
引用
收藏
页码:767 / 771
页数:5
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