A new Claisen sequence for the synthesis of 3-substituted-2-oxindoles

被引：50

作者：

Booker-Milburn, KI

Fedouloff, M

Paknoham, SJ

Strachan, JB

Melville, JL

Voyle, M

机构：

[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England

[2] SmithKline Beecham Pharmaceut, Harlow CM19 5AW, Essex, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 23期

关键词：

D O I：

10.1016/S0040-4039(00)00649-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of 3-methoxycarbonylindole with N-chlorosuccinimide followed by a range of alkenols yields 3-allylated-2-oxindoles in good yield, via a novel addition-Claisen rearrangement sequence. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：4657 / 4661

页数：5

共 6 条

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[4] SAKAMOTO M, 1996, TETRAHEDRON LETT, V37, P7525
[5] The chemistry of indoles Part 86 - A novel synthetic method of pyrrolo[2,3-b]indoles and its application to the synthesis of (+/-)-debromoflustramine B
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[J]. HETEROCYCLES, 1997, 45 (12) : 2327 - 2330
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