Towards a bacterial treatment for armpit malodour

被引:38
作者
Callewaert, Chris [1 ,2 ]
Lambert, Jo [3 ]
Van de Wiele, Tom [1 ]
机构
[1] Univ Ghent, Ctr Microbial Ecol & Technol CMET, Ghent, Belgium
[2] Univ Calif San Diego, Dept Pediat & Comp Sci & Engn, La Jolla, CA 92093 USA
[3] Ghent Univ Hosp, Dept Dermatol, Ghent, Belgium
基金
比利时弗兰德研究基金会;
关键词
armpit; body odour; microbiome; probiotics; transplantation; MICROBIOME; GLANDS;
D O I
10.1111/exd.13259
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100227 [皮肤病学];
摘要
Axillary malodour is a frustrating condition for many people. It can lead to significant discomforts and various psychological effects. The underarm microbiome plays a major role in axillary malodour formation. Not only the bacteria on the epidermis, but also and especially those living in the sweat glands, sweat pores and hair follicles play a pivotal role in malodour development. To treat underarm malodour, this viewpoint article envisions a bacterial treatment. Replacing the autochthonous malodour-causing microbiome with a non-odour-causing microbiome, through an armpit bacterial transplantation or direct application of probiotics/non-odour-causing bacteria, could resolve the condition. Selective steering of the microbiome with prebiotics, biochemicals or plant extracts can likewise greatly help in improving the underarm odour. Elimination/inhibition of the bad bugs and application/stimulation of the good bugs will be part of the future treatment for axillary body odour.
引用
收藏
页码:388 / 391
页数:4
相关论文
共 9 条
[1]
Identification of axillary Staphylococcus sp involved in the production of the malodorous thioalcohol 3-methyl-3-sufanylhexan-1-ol [J].
Bawdon, Daniel ;
Cox, Diana S. ;
Ashford, David ;
James, A. Gordon ;
Thomas, Gavin H. .
FEMS MICROBIOLOGY LETTERS, 2015, 362 (16)
[2]
Characterization of Staphylococcus and Corynebacterium Clusters in the Human Axillary Region [J].
Callewaert, Chris ;
Kerckhof, Frederiek-Maarten ;
Granitsiotis, Michael S. ;
Van Gele, Mireille ;
Van de Wiele, Tom ;
Boon, Nico .
PLOS ONE, 2013, 8 (08)
[3]
THE EVOLUTION OF SWEAT GLANDS [J].
FOLK, GE ;
SEMKEN, HA .
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY, 1991, 35 (03) :180-186
[4]
STRUCTURAL-CHANGES IN AXILLARY ECCRINE GLANDS FOLLOWING LONG-TERM TREATMENT WITH ALUMINUM-CHLORIDE HEXAHYDRATE SOLUTION [J].
HOLZLE, E ;
BRAUNFALCO, O .
BRITISH JOURNAL OF DERMATOLOGY, 1984, 110 (04) :399-403
[5]
HSV-1 exploits the innate immune scavenger receptor MARCO to enhance epithelial adsorption and infection [J].
MacLeod, Daniel T. ;
Nakatsuji, Teruaki ;
Yamasaki, Kenshi ;
Kobzik, Lester ;
Gallo, Richard L. .
NATURE COMMUNICATIONS, 2013, 4
[6]
Stool substitute transplant therapy for the eradication of Clostridium difficile infection: 'RePOOPulating' the gut [J].
Petrof, Elaine O. ;
Gloor, Gregory B. ;
Vanner, Stephen J. ;
Weese, Scott J. ;
Carter, David ;
Daigneault, Michelle C. ;
Brown, Eric M. ;
Schroeter, Kathleen ;
Allen-Vercoe, Emma .
MICROBIOME, 2013, 1
[7]
Mapping axillary microbiota responsible for body odours using a culture-independent approach [J].
Troccaz, Myriam ;
Gaia, Nadia ;
Beccucci, Sabine ;
Schrenzel, Jacques ;
Cayeux, Isabelle ;
Starkenmann, Christian ;
Lazarevic, Vladimir .
MICROBIOME, 2015, 3
[8]
The effect of habitual and experimental antiperspirant and deodorant product use on the armpit microbiome [J].
Urban, Julie ;
Fergus, Daniel J. ;
Savage, Amy M. ;
Ehlers, Megan ;
Menninger, Holly L. ;
Dunn, Robert R. ;
Horvath, Julie E. .
PEERJ, 2016, 4
[9]
Microbiome dynamics of human epidermis following skin barrier disruption [J].
Zeeuwen, Patrick L. J. M. ;
Boekhorst, Jos ;
van den Bogaard, Ellen H. ;
de Koning, Heleen D. ;
van de Kerkhof, Peter M. C. ;
Saulnier, Delphine M. ;
van Swam, Iris I. ;
van Hijum, Sacha A. F. T. ;
Kleerebezem, Michiel ;
Schalkwijk, Joost ;
Timmerman, Harro M. .
GENOME BIOLOGY, 2012, 13 (11)