Cavernosolide, a new sesterterpene from a Tyrrhenian sponge

被引：25

作者：

DeRosa, S

Crispino, A

DeGiulio, A

Iodice, C

Tommonaro, G

机构：

[1] ICMIB CNR, 80072 Arco Felice Napoli

来源：

JOURNAL OF NATURAL PRODUCTS | 1997年 / 60卷 / 08期

关键词：

D O I：

10.1021/np970183b

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Cavernosolide (3a), a new sesterterpene, has been isolated from the Tyrrhenian sponge Fasciospongia cavernosa. The structure was proposed on the basis of spectroscopic data and by chemical transformations. Cavernosolide showed potent activity (LC50 = 0.37 mu g/mL) in the Artemia salina bioassay and a moderate toxicity (LC50 = 0.75 mu g/mL) in a fish (Gambusia affinis) lethality assay.

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页码：844 / 846

页数：3

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