Irreversible, direct bonding of nanoporous polymer membranes to PDMS or glass microdevices

被引：137

作者：

Aran, Kiana ^{[1
]}

Sasso, Lawrence A. ^{[1
]}

Kamdar, Neal ^{[1
]}

Zahn, Jeffrey D. ^{[1
]}

机构：

[1] Rutgers State Univ, Dept Biomed Engn, Piscataway, NJ 08854 USA

来源：

LAB ON A CHIP | 2010年 / 10卷 / 05期

基金：

美国国家卫生研究院;

关键词：

SYSTEMS; ARRAY;

D O I：

10.1039/b924816a

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A method for integrating porous polymer membranes such as polycarbonate, polyethersulfone and polyethylene terephthalate to microfluidic devices is described. The use of 3-amino-propyltriethoxysilane as a chemical crosslinking agent was extended to integrate membranes with PDMS and glass microfluidic channels. A strong, irreversible bond between the membranes and microfluidic structure was achieved. The bonding strength in the APTES treated devices was significantly greater than in devices fabricated using either a PDMS "glue'' or two-part epoxy bonding method. Evaluation of a filtering microdevice and the pore structure via SEM indicates the APTES conjugation does not significantly alter the membrane transport function and pore morphology.

引用

页码：548 / 552

页数：5

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