Correlation between histological invasiveness and the computed tomography value in pure ground-glass nodules

被引：132

作者：

Kitami, Akihiko ^{[1
]}

Sano, Fumitoshi ^{[1
]}

Hayashi, Shoko ^{[1
]}

Suzuki, Kosuke ^{[1
]}

Uematsu, Shugo ^{[1
]}

Kamio, Yoshito ^{[1
]}

Suzuki, Takashi ^{[1
]}

Kadokura, Mitsutaka ^{[3
]}

Omatsu, Mutsuko ^{[2
]}

Kunimura, Toshiaki ^{[2
]}

机构：

[1] Showa Univ, Northern Yokohama Hosp, Resp Dis Ctr, Tsuzuki Ku, 35-1 Chigasaki Chuo, Yokohama, Kanagawa 2248503, Japan

[2] Showa Univ, Northern Yokohama Hosp, Dept Clin Diagnost Pathol, Yokohama, Kanagawa 2248503, Japan

[3] Showa Univ, Sch Med, Div Chest Surg, Tokyo 142, Japan

来源：

SURGERY TODAY | 2016年 / 46卷 / 05期

关键词：

Lung cancer; Diagnosis; Surgery; Computed tomography; LUNG ADENOCARCINOMA; PROGNOSTIC-SIGNIFICANCE; INTERNATIONAL-ASSOCIATION; CT FINDINGS; OPACITY; CLASSIFICATION; CANCER; PROGRESSION; MANAGEMENT; CARCINOMA;

D O I：

10.1007/s00595-015-1208-1

中图分类号：

R61 [外科手术学];

学科分类号：

100210 [外科学];

摘要：

The purpose of this study was to evaluate the correlation between histological invasiveness and the computed tomography (CT) value and size in pure ground-glass nodules (GGNs) to determine optimal "follow-up or resection" strategies. Between 2001 and 2014, 78 resected, pure GGNs were retrospectively evaluated. The maximum diameter and CT value of pure GGNs were measured using a computer graphics support system. All GGNs with a maximum diameter a parts per thousand currency sign10 mm and CT value a parts per thousand currency signa'600 Hounsfield units (HU) were considered to be noninvasive lesions, while 21 of 26 (81 %) with a maximum diameter > 10 mm and CT value >-600 HU were considered to be invasive lesions. With respect to the correlation between each histological type and pure GGN with a maximum diameter a parts per thousand currency sign10 mm and CT value a parts per thousand currency signa'600 HU, the specificity was 90 % and the sensitivity and negative predictive value were both 100 % in atypical adenomatous hyperplasia (AAH), while the specificity was 58 % and the sensitivity and positive predictive value were 0 % in minimally invasive and invasive adenocarcinoma. Pure GGNs with a maximum diameter of a parts per thousand currency sign10 mm and CT value of a parts per thousand currency signa'600 HU are nearly always pre-invasive lesions; therefore, surgery should be carefully selected in such patients.

引用

页码：593 / 598

页数：6

共 25 条

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A clinicopathological study of resected subcentimeter lung cancers: A favorable prognosis for ground glass opacity lesions [J].