Integrated multiplexed biosensors based on liquid core optical ring resonators and antiresonant reflecting optical waveguides

被引:104
作者
White, Ian M.
Oveys, Hesam
Fan, Xudong [1 ]
Smith, Terry L.
Zhang, Junying
机构
[1] Univ Missouri, Biol Engn Dept, Columbia, MO 65211 USA
[2] 3M Co, Corp Res Mat Labs, St Paul, MN 55144 USA
关键词
D O I
10.1063/1.2387112
中图分类号
O59 [应用物理学];
学科分类号
摘要
The authors demonstrate integrated biosensors utilizing antiresonant reflecting optical waveguides (ARROWs) to excite the whispering gallery modes of a liquid core optical ring resonator (LCORR) sensor. Because this architecture is based on integration, it is robust and well suited for dense multiplexing of sensors. They analytically and experimentally characterize the coupling between the ARROW structure and the LCORR and show good agreement between the coupling theory and experimental results. The multiplexing capability is experimentally demonstrated by exciting multiple ring resonators along a single LCORR using the ARROW array. Also, they show the label-free detection of bovine serum albumin with this LCORR-ARROW system.
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页数:3
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