The bladder extracellular matrix. Part II: regenerative applications

被引：32

作者：

Aitken, Karen J. ^{[1
,2
]}

Baegli, Darius J. ^{[1
,2
]}

机构：

[1] Univ Toronto, Hosp Sick Children, Div Dev & Stem Cell Biol, Toronto, ON M5G 1X8, Canada

[2] Univ Toronto, Hosp Sick Children, Div Urol, Toronto, ON M5G 1X8, Canada

来源：

NATURE REVIEWS UROLOGY | 2009年 / 6卷 / 11期

基金：

加拿大健康研究院;

关键词：

MESENCHYMAL STEM-CELLS; SMOOTH-MUSCLE-CELLS; BIOLOGICAL VASCULARIZED MATRIX; SMALL-INTESTINAL SUBMUCOSA; BONE-MARROW; HYALURONIC-ACID; URINARY-TRACT; IN-VITRO; PROGENITOR CELLS; DIRECTED DIFFERENTIATION;

D O I：

10.1038/nrurol.2009.202

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

100201 [内科学]; 100221 [泌尿外科学];

摘要：

Bladder regeneration is a long-sought goal that could provide alternatives to cystoplasty using nonurological tissues. Regeneration might be achieved in different ways, such as seeding matrices with stem cells or conventional cells, or repopulation of the matrix by the body's own reservoir of cells. Consideration of how the extracellular matrix directs cell behavior will be crucial to the success of regenerative therapies.

引用

收藏

页码：612 / 621

页数：10

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