Residue analysis: Future trends from a historical perspective

被引：77

作者：

De Brabander, H. F. ^{[1
]}

Noppe, H. ^{[1
]}

Verheyden, K. ^{[1
]}

Bussche, J. Vanden ^{[1
]}

Wille, K. ^{[1
]}

Okerman, L. ^{[1
]}

Vanhaecke, L. ^{[1
]}

Reybroeck, W. ^{[2
]}

Ooghe, S. ^{[2
]}

Croubels, S. ^{[3
]}

机构：

[1] Univ Ghent, Fac Vet Med, Dept Vet Publ Hlth & Food Safety, Lab Chem Anal,Res Grp Vet Publ Hlth & Zoonoses, B-9820 Merelbeke, Belgium

[2] Inst Agr & Fisheries Res, Technol & Food Unit, B-9090 Melle, Belgium

[3] Univ Ghent, Fac Vet Med, Dept Pharmacol Toxicol & Biochem, B-9820 Merelbeke, Belgium

来源：

JOURNAL OF CHROMATOGRAPHY A | 2009年 / 1216卷 / 46期

关键词：

Residues; Banned substances; Veterinary medicinal products; TANDEM MASS-SPECTROMETRY; PERFORMANCE LIQUID-CHROMATOGRAPHY; SOLID-PHASE EXTRACTION; VETERINARY DRUG RESIDUES; RECOMBINANT BOVINE SOMATOTROPIN; SUPERCRITICAL-FLUID EXTRACTION; ACCELERATED SOLVENT-EXTRACTION; NEGATIVE CHEMICAL-IONIZATION; BETA-LACTAM ANTIBIOTICS; ANABOLIC-STEROIDS RESIDUES;

D O I：

10.1016/j.chroma.2009.02.027

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A residue is a trace (mu g kg(-1), ng kg(-1)) of a substance, present in a matrix. Residue analysis is a relatively young discipline and a very broad area, including banned (A) substances as well as registered veterinary medicinal products (B substances). The objective of this manuscript is to review future trends in the analysis of residues of veterinary drugs in meat producing animals out of historical perspectives. The analysis of residues in meat producing animals has known a tremendous evolution during the past 35-40 years. In the future, it can be foreseen that this evolution will proceed in the direction of the use of more and more sophisticated and expensive machines. These apparatus, and the necessary human resources for their use, will only be affordable for laboratories with sufficient financial resources and having guarantee for a sufficient throughput of samples. (C) 2009 Elsevier B.V. All rights reserved

引用

页码：7964 / 7976

页数：13

共 303 条

[1] Determination of diclofenac sodium, flufenamic acid, indomethacin and ketoprofen by LC-APCI-MS [J].