Diterpenoids from Euphorbia peplus

被引:61
作者
Hohmann, J
Evanics, F
Berta, L
Bartók, T
机构
[1] Albert Szent Gyorgyi Med Univ, Dept Pharmacognosy, H-6701 Szeged, Hungary
[2] Albert Szent Gyorgyi Med Univ, Dept Pharmaceut Anal, H-6701 Szeged, Hungary
[3] Cereal Res Non Profit Co, Szeged, Hungary
关键词
D O I
10.1055/s-2000-8568
中图分类号
Q94 [植物学];
学科分类号
071001 [植物学];
摘要
From a pro-inflammatory active extract of Euphorbia peplus, two new diterpene polyesters based on the pepluane and jatrophane skeletons were isolated, together with four known ingenane and jatrophane diterpenes. The structures were determined on the basis of extensive NMR studies. Ingenol 3-angelate, which was obtained for the first time from this plant, is an irritant toxin with high activity.
引用
收藏
页码:291 / 294
页数:4
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