Multimodal cell imaging by ruthenium polypyridyl labelled cell penetrating peptides

被引：85

作者：

Cosgrave, Lynda ^{[1
]}

Devocelle, Marc ^{[2
]}

Forster, Robert J. ^{[2
]}

Keyes, Tia E. ^{[1
]}

机构：

[1] Dublin City Univ, Sch Chem Sci, Natl Ctr Sensor Res, Natl Bioimaging Platform, Dublin 9, Ireland

[2] Royal Coll Surgeons Ireland, Dept Pharmaceut & Med Chem, Ctr Synth & Chem Biol, Dublin 2, Ireland

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 01期

基金：

爱尔兰科学基金会;

关键词：

LIGHT-SWITCH; COMPLEXES; PROBES; DNA;

D O I：

10.1039/b918611e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The capacity of ruthenium polypyridyl complexes as probes for combined confocal luminescence and resonance Raman imaging, enabled by their large Stokes shift, is demonstrated for a novel membrane sensitive Ru(II) polypyridyl peptide. Confocal luminescence and resonance Raman imaging provides complementary information about the membrane phospholipid regions of the cell and the location of the dye within the cell.

引用

页码：103 / 105

页数：3

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