Chemical microarrays to identify ligands that bind pathogenic cells

被引：13

作者：

Barrett, Olivia J.

Childs, Jessica L.

Disney, Matthew D. ^{[1
]}

机构：

[1] SUNY Buffalo, Ctr Excellence Bioinformat & Life Sci, Buffalo, NY 14260 USA

[2] SUNY Buffalo, Dept Chem, Buffalo, NY 14260 USA

来源：

CHEMBIOCHEM | 2006年 / 7卷 / 12期

关键词：

biosensors; cell adhesion; microarrays; molecular recognition; pathogens;

D O I：

10.1002/cbic.200600260

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Tryptamine trial. Chemical microarrays have been used to identify ligands that recognize the surface of a variety of pathogenic organisms. In each case, the highest affinity ligand is tryptamine, which is shown to recognize cell surfaces when multivalently displayed on a microarray surface or on a water-soluble polymer. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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收藏

页码：1882 / 1885

页数：4

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