Astaxanthin production by Phaffia rhodozyma enhanced in fed-batch culture with glucose and ethanol feeding

被引：90

作者：

Yamane, Y ^{[1
]}

Higashida, K ^{[1
]}

Nakashimada, Y ^{[1
]}

Kakizono, T ^{[1
]}

Nishio, N ^{[1
]}

机构：

[1] HIROSHIMA UNIV,FAC ENGN,DEPT FERMENTAT TECHNOL,HIGASHIHIROSHIMA 739,JAPAN

来源：

BIOTECHNOLOGY LETTERS | 1997年 / 19卷 / 11期

关键词：

D O I：

10.1023/A:1018492611011

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];

摘要：

Of various carbon sources, examined for the cultivation of Phaffia rhodozyma, ethanol enhanced the astaxanthin content but severely decreased growth. Therefore, high cell mass was obtained by glucose fed-batch culture with pH-stat, and the ethanol feeding was performed based on DO-stat. As a result of this two-stage fed-batch cultivation, 30 g dry cells per liter were obtained, and the astaxanthin content reached 0.72 mg/g, which was 2.2-fold higher than that without ethanol feeding.

引用

页码：1109 / 1111

页数：3

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