Mechanism of the redox reaction of the Aequorea green fluorescent protein (GFP)

被引：26

作者：

Kojima, S

Hirano, T

Niwa, H

Ohashi, M

Inouye, S

Tsuji, FL

机构：

[1] UNIV ELECTROCOMMUN,DEPT APPL PHYS & CHEM,CHOFU,TOKYO 182,JAPAN

[2] CHISSO CORP,YOKOHAMA RES CTR,KANAZAWA KU,YOKOHAMA,KANAGAWA 236,JAPAN

[3] UNIV CALIF SAN DIEGO,SCRIPPS INST OCEANOG,MARINE BIOL RES DIV 0202,LA JOLLA,CA 92093

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 16期

关键词：

D O I：

10.1016/S0040-4039(97)00486-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A model compound, 4-(4-hydroxyphenyl)methylideneimidazol-5-one undergoes a reversible redox reaction identical to that of the Aequorea green fluorescent protein (GFP), strongly suggesting that the GFP chromophore is derived via the autoxidation of a nonfluorescent dihydro precursor in dihydro-GFP. (C) 1997 Elsevier Science Ltd.

引用

页码：2875 / 2878

页数：4

共 26 条

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