Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease

被引：456

作者：

Agusti, Alvar ^{[1
,2
,3
]}

Hogg, James C. ^{[4
]}

机构：

[1] Inst Invest Agusti Pi i Sunyer, Resp Inst, Hosp Clin, Barcelona, Spain

[2] Univ Barcelona, Barcelona, Spain

[3] Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Resp, Madrid, Spain

[4] Univ British Columbia, St Pauls Hosp, Ctr Heart & Lung Innovat, Vancouver, BC, Canada

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2019年 / 381卷 / 13期

关键词：

SMALL-AIRWAY OBSTRUCTION; LUNG-FUNCTION; NATURAL-HISTORY; DNA METHYLATION; GLOBAL STRATEGY; EMPHYSEMA; SMOKERS; INFLAMMATION; COPD; HYPERTENSION;

D O I：

10.1056/NEJMra1900475

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

A pair of review articles examines our current understanding of the biology, diagnosis, and treatment of chronic obstructive pulmonary disease. This article focuses on the pathogenesis of COPD.

引用

页码：1248 / 1256

页数：9

共 73 条

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[2]

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