Trends in miniaturized total analysis systems for point-of-care testing in clinical chemistry

被引:337
作者
Tüdos, AJ
Besselink, GAJ
Schasfoort, RBM
机构
[1] NIZO Food Res, NL-6718 ZB Ede, Netherlands
[2] Univ Twente, MESA Res Inst, NL-7500 AE Enschede, Netherlands
关键词
D O I
10.1039/b106958f
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A currently emerging approach enables more widespread monitoring of health parameters in disease prevention and biomarker monitoring. Miniaturisation provides the means for the production of small, fast and easy-to-operate devices for reduced-cost healthcare testing at the point-of-care (POC) or even for household use. A critical overview is given on the present state and requirements of POC testing, on muTAS elements suited for implementation in future muTAS devices for POC testing and muTAS systems for the determination of clinical parameters.
引用
收藏
页码:83 / 95
页数:13
相关论文
共 169 条
[11]   Implementation of an integrated instrument control and data management system for point of care blood gas testing [J].
Bernard, D ;
Vanhee, D ;
Blaton, V .
CLINICA CHIMICA ACTA, 2001, 307 (1-2) :169-173
[12]   Blood gases and oximetry: calibration-free new dry-chemistry and optical technology for near-patient testing [J].
Boalth, N ;
Wandrup, J ;
Larsson, L ;
Frischauf, PA ;
Lundsgaard, FC ;
Andersen, WL ;
Jensen, NH ;
Singer, R ;
Troldborg, CP ;
Lunding, G .
CLINICA CHIMICA ACTA, 2001, 307 (1-2) :225-233
[13]   A flow-through amperometric sensor based on dialysis tubing and free enzyme reactors [J].
Böhm, S ;
Pijanowska, D ;
Olthuis, W ;
Bergveld, P .
BIOSENSORS & BIOELECTRONICS, 2001, 16 (06) :391-397
[14]   A plastic micropump constructed with conventional techniques and materials [J].
Böhm, S ;
Olthuis, W ;
Bergveld, P .
SENSORS AND ACTUATORS A-PHYSICAL, 1999, 77 (03) :223-228
[15]   A flow-through cell with integrated coulometric pH actuator [J].
Bohm, S ;
Olthuis, W ;
Bergveld, P .
SENSORS AND ACTUATORS B-CHEMICAL, 1998, 47 (1-3) :48-53
[16]  
BOHM S, 2000, THESIS U TWENTE NETH
[17]   Microfabricated silicon mixers for submillisecond quench-flow analysis [J].
Bökenkamp, D ;
Desai, A ;
Yang, X ;
Tai, YC ;
Marzluff, EM ;
Mayo, SL .
ANALYTICAL CHEMISTRY, 1998, 70 (02) :232-236
[18]  
BOONE TD, 1998, MICRO TOTAL ANAL SYS, P257
[19]   Diffusion-based extraction in a microfabricated device [J].
Brody, JP ;
Yager, P .
SENSORS AND ACTUATORS A-PHYSICAL, 1997, 58 (01) :13-18
[20]  
Bruin GJM, 2000, ELECTROPHORESIS, V21, P3931, DOI 10.1002/1522-2683(200012)21:18<3931::AID-ELPS3931>3.0.CO