Oxidative cleavage of 3-alkoxy-2,5-dihydrofurans and its application to the de novo synthesis of rare monosaccharides as exemplified by L-cymarose

被引：38

作者：

Brasholz, Malte ^{[1
]}

Reissig, Hans-Ulrich ^{[1
]}

机构：

[1] Free Univ Berlin, Inst Chem & Biochem, D-14195 Berlin, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 10期

关键词：

allenes; carbohydrates; oxidation; oxygen heterocycles; reduction;

D O I：

10.1002/anie.200604078

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Donor-substituted α,β-unsaturated γ-keto aldehydes can be formed by the selective oxidative cleavage of 3-alkoxy-2,5-dihydrofurans. These 1,4-dicarbonyl compounds are highly suitable building blocks for the synthesis of rare sugars, for example, the dideoxypyranose L-cymarose (see scheme). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1634 / 1637

页数：4

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