Regulation of expression of methane monooxygenases by copper ions

被引：193

作者：

Murrell, JC ^{[1
]}

McDonald, IR ^{[1
]}

Gilbert, B ^{[1
]}

机构：

[1] Univ Warwick, Dept Biol Sci, Coventry CV4 7AL, W Midlands, England

来源：

TRENDS IN MICROBIOLOGY | 2000年 / 8卷 / 05期

基金：

英国生物技术与生命科学研究理事会; 英国自然环境研究理事会;

关键词：

D O I：

10.1016/S0966-842X(00)01739-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Many methanotrophs contain both a soluble and a particulate methane monooxygenase. A unique metabolic switch, mediated by copper ions, regulates the expression of these enzymes. When the copper-to-biomass ratio of the cell is low, the soluble enzyme is expressed, and when the copper-to-biomass ratio is high, the particulate enzyme is expressed. A model for the mechanism of this switch is proposed.

引用

页码：221 / 225

页数：5

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