The importance of efflux pumps in bacterial antibiotic resistance

被引：527

作者：

Webber, MA ^{[1
]}

Piddock, LJV ^{[1
]}

机构：

[1] Univ Birmingham, Div Immun & Infect, Antimicrobial Agents Res Grp, Birmingham B15 2TT, W Midlands, England

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2003年 / 51卷 / 01期

关键词：

efflux; multiple antibiotic resistance;

D O I：

10.1093/jac/dkg050

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

[No abstract available]

引用

页码：9 / 11

页数：3

共 33 条

[1] The MexR repressor of the mexAB-oprM multidrug efflux operon in Pseudomonas aeruginosa:: Characterization of mutations compromising activity [J].

Adewoye, L ;

Sutherland, A ;

Srikumar, R ;

Poole, K .

JOURNAL OF BACTERIOLOGY, 2002, 184 (15) :4308-4312

[2] Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon [J].

Alekshun, MN ;

Levy, SB .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (10) :2067-2075

[3] Cross-resistance between triclosan and antibiotics in Pseudomonas aeruginosa is mediated by multidrug efflux pumps:: Exposure of a susceptible mutant strain to triclosan selects nfxB mutants overexpressing MexCD-OprJ [J].

Chuanchuen, R ;

Beinlich, K ;

Hoang, TT ;

Becher, A ;

Karkhoff-Schweizer, RR ;

Schweizer, HP .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (02) :428-432

[4] CROSS-RESISTANCE TO FLUOROQUINOLONES IN MULTIPLE-ANTIBIOTIC-RESISTANT (MAR) ESCHERICHIA-COLI SELECTED BY TETRACYCLINE OR CHLORAMPHENICOL - DECREASED DRUG ACCUMULATION ASSOCIATED WITH MEMBRANE-CHANGES IN ADDITION TO OMPF REDUCTION [J].

COHEN, SP ;

MCMURRY, LM ;

HOOPER, DC ;

WOLFSON, JS ;

LEVY, SB .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1989, 33 (08) :1318-1325

[5] Biocide abuse and antimicrobial resistance: being clear about the issues - Reply [J].

Fraise, AP .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2002, 50 (01) :139A-139A

[6] Biocide abuse and antimicrobial resistance - a cause for concern? [J].

Fraise, AP .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2002, 49 (01) :11-12

[7] Biocide abuse and antimicrobial resistance: being clear about the issues [J].

Gilbert, P ;

McBain, AJ ;

Bloomfield, SF .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2002, 50 (01) :137-139

[8] Identification of an efflux pump gene, pmrA, associated with fluoroquinolone resistance in Streptococcus pneumoniae [J].

Gill, MJ ;

Brenwald, NP ;

Wise, R .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (01) :187-189

[9] INDUCIBLE NORA-MEDIATED MULTIDRUG-RESISTANCE IN STAPHYLOCOCCUS-AUREUS [J].

KAATZ, GW ;

SEO, SM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (12) :2650-2655

[10] Non-target gene mutations in the development of fluoroquinolone resistance in Escherichia coli [J].

Kern, WV ;

Oethinger, M ;

Jellen-Ritter, AS ;

Levy, SB .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (04) :814-820

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