Cloning and expression of human cDNA encoding Na+,K+-ATPase gamma-subunit

被引：32

作者：

Kim, JW ^{[1
]}

Lee, Y ^{[1
]}

Lee, IA ^{[1
]}

Kang, HB ^{[1
]}

Choe, YK ^{[1
]}

Choe, IS ^{[1
]}

机构：

[1] KIST,MOL & CELLULAR BIOL RES GRP,TAEJON 305600,SOUTH KOREA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1997年 / 1350卷 / 02期

关键词：

ATPase; Na+/K+-; gamma subunit; cDNA sequence; tissue distribution; (human);

D O I：

10.1016/S0167-4781(96)00219-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A cDNA clone encoding the Na+,K+-Atpase gamma-subunit polypeptide was cloned from a human fetal liver cDNA library. The deduced amino acid sequence of the protein comprised 58 amino acids with a calculated molecular weight of 6400 Da, and showed about 86% homology when compared with those of the bovine, rat and mouse Na+,K+-ATPase gamma-subunits published elsewhere. Northern blot analysis showed that the cDNA hybridized to a 0.7 kb mRNA which was expressed in human kidney, pancreas and fetal liver.

引用

页码：133 / 135

页数：3

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