Fatal co-infection with swine origin influenza virus A/H1N1 and community-acquired methicillin-resistant Staphylococcus aureus

被引:28
作者
Cheng, Vincent C. C.
Lau, Yuk-Kong [2 ]
Lee, Kwok-Lun [2 ]
Yiu, Kwan-Ho [3 ]
Chan, Kwok-Hung
Ho, Pak-Leung
Yuen, Kwok-Yung [1 ]
机构
[1] Univ Hong Kong, Dept Microbiol, Carol Yu Ctr Infect, Queen Mary Hosp, Pokfulam, Hong Kong, Peoples R China
[2] Ruttonjee & Tang Shiu Kin Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
[3] Pamela Youde Nethersole Eastern Hosp, Dept Pathol, Hong Kong, Hong Kong, Peoples R China
关键词
Swine origin influenza virus A/H1N1; CA-MRSA; Pneumonia; Multiplex PCR; PANTON-VALENTINE LEUKOCIDIN; A H1N1 VIRUS; PNEUMONIA; HEALTHY;
D O I
10.1016/j.jinf.2009.08.021
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) co-infection has been described previously in association with respiratory tract infection caused by seasonal influenza A viruses, but not with swine origin influenza A (H1N1) virus (S-OIV). We report the clinical and pathological findings of the first death with fulminant co-infection by CA-MRSA. Since early empirical treatment with beta-lactam plus fluoroquinolone or macrolides is often initiated before specimen collections, bacterial co-infection in S-OIV may have been under-reported. (c) 2009 The British Infection Society. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:366 / 370
页数:5
相关论文
共 22 条
[1]  
[Anonymous], 2009, Wkly Epidemiol Rec, V84, P301
[2]  
Battegay M, 2020, SWISS MED WKLY, V150, DOI [10.4414/smw.w20203, 10.4414/smw.2020.20203]
[3]   Comparison of the NucliSens easyMAG and Qiagen BioRobot 9604 nucleic acid extraction systems for detection of RNA and DNA respiratory viruses in nasopharyngeal aspirate samples [J].
Chan, Kwok Hung ;
Yam, Wing Cheong ;
Pang, Chiu Mei ;
Chan, Kit Man ;
Lam, Siu Yan ;
Lo, Kam Fai ;
Poon, Leo L. M. ;
Peiris, J. S. Malik .
JOURNAL OF CLINICAL MICROBIOLOGY, 2008, 46 (07) :2195-2199
[4]   Binding of bacteria to HEp-2 cells infected with influenza A virus [J].
El Ahmer, OR ;
Raza, MW ;
Ogilvie, MM ;
Weir, DM ;
Blackwell, CC .
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, 1999, 23 (04) :331-341
[5]  
ELSTON JW, 2009, J INFECT 0704
[6]  
FAIX DJ, 2009, N ENGL J MED 0629
[7]   Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients [J].
Gillet, Y ;
Issartel, B ;
Vanhems, P ;
Fournet, JC ;
Lina, G ;
Bes, M ;
Vandenesch, F ;
Piémont, Y ;
Brousse, N ;
Floret, D ;
Etienne, J .
LANCET, 2002, 359 (9308) :753-759
[8]   Changes in the prevalence of nasal colonization with Staphylococcus aureus in the United States, 2001-2004 [J].
Gorwitz, Rachel J. ;
Kruszon-Moran, Deanna ;
McAllister, Sigrid K. ;
McQuillan, Geraldine ;
McDougal, Linda K. ;
Fosheim, Gregory E. ;
Jensen, Bette J. ;
Killgore, George ;
Tenover, Fred C. ;
Kuehnert, Matthew J. .
JOURNAL OF INFECTIOUS DISEASES, 2008, 197 (09) :1226-1234
[9]  
Napolitano L. M., 2009, Morbidity and Mortality Weekly Report, V58, P749
[10]   Severe community-acquired pneumonia due to Staphylococcus aureus, 2003-04 influenza season [J].
Hageman, Jeffrey C. ;
Uyeki, Timothy M. ;
Francis, John S. ;
Jernigan, Daniel B. ;
Wheeler, J. Gary ;
Bridges, Carolyn B. ;
Barenkamp, Stephen J. ;
Sievert, Dawn M. ;
Srinivasan, Arjun ;
Doherty, Meg C. ;
McDougal, Linda K. ;
Killgore, George E. ;
Lopatin, Uri A. ;
Coffman, Rebecca ;
MacDonald, J. Kathryn ;
McAllister, Sigrid K. ;
Fosheim, Gregory E. ;
Patel, Jean B. ;
McDonald, L. Clifford .
EMERGING INFECTIOUS DISEASES, 2006, 12 (06) :894-899