Copper-catalyzed aerobic oxidation of alcohols under fluorous biphasic conditions

被引：192

作者：

Betzemeier, B

Cavazzini, M

Quici, S

Knochel, P

机构：

[1] Univ Munich, Inst Organ Chem, D-81377 Munich, Germany

[2] CNR, Ctr Sintesi & Stereochim Specali Sistemi Organ, I-20133 Milan, Italy

[3] CNR, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 22期

关键词：

bipyridine; copper; fluorous phase; oxidation; TEMPO;

D O I：

10.1016/S0040-4039(00)00620-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A catalytic amount of perfluoroalkyl substituted bipyridine 1 (2 mol%), CuBr . Me2S (2 mol%) and TEMPO (3.5 mol%) allow the oxidation of various alcohols to aldehydes and ketones in a fluorous biphasic system of chlorobenzene and perfluorooctane directly with oxygen. The catalyst can be used for several reaction runs without a loss of reactivity. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：4343 / 4346

页数：4