The biology of photodynamic therapy

被引：81

作者：

Moore, JV ^{[1
]}

West, CML ^{[1
]}

Whitehurst, C ^{[1
]}

机构：

[1] CHRISTIE HOSP NHS TRUST, DEPT EXPT RADIAT ONCOL, PATERSON INST CANC RES, MANCHESTER M20 4BX, LANCS, ENGLAND

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 1997年 / 42卷 / 05期

关键词：

D O I：

10.1088/0031-9155/42/5/012

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The subcellular, cellular and tissue/tumour interactions with non-toxic photosensitizing chemicals plus non-thermal visible light (photodynamic therapy (PDT)) are reviewed. The extent to which endothelium/vasculature is the primary target is discussed, and the biochemical opportunities for manipulating outcome highlighted. The nature of tumour destruction by PDT lends itself to imaging outcome by MRI and PET.

引用

收藏

页码：913 / 935

页数：23

相关论文

共 183 条

[91]

Kaye Andrew H., 1993, Annals Academy of Medicine Singapore, V22, P470

[92] QUANTITATIVE MRI OF GD-DTPA UPTAKE IN TUMORS - RESPONSE TO PHOTODYNAMIC THERAPY [J].

KENNEDY, SD ;

SZCZEPANIAK, LS ;

GIBSON, SL ;

HILF, R ;

FOSTER, TH ;

BRYANT, RG .

MAGNETIC RESONANCE IN MEDICINE, 1994, 31 (03) :292-301

[93]

KESSEL D, 1981, CANCER RES, V41, P1318

[94] SITES OF PHOTOSENSITIZATION BY DERIVATIVES OF HEMATOPORPHYRIN [J].

KESSEL, D .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1986, 44 (04) :489-493

[95] MODES OF PHOTODYNAMIC VS SONODYNAMIC CYTOTOXICITY [J].

KESSEL, D ;

LO, J ;

JEFFERS, R ;

FOWLKES, JB ;

CAIN, C .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 1995, 28 (03) :219-221

[96] SELECTIVE PHOTODYNAMIC INACTIVATION OF A MULTIDRUG TRANSPORTER BY A CATIONIC PHOTOSENSITIZING AGENT [J].

KESSEL, D ;

WOODBURN, K .

BRITISH JOURNAL OF CANCER, 1995, 71 (02) :306-310

[97] EFFECTS OF PHOTOACTIVATED PORPHYRINS AT CELL-SURFACE OF LEUKEMIA L1210-CELLS [J].

KESSEL, D .

BIOCHEMISTRY, 1977, 16 (15) :3443-3449

[98]

KICK G, 1995, CANCER RES, V55, P2373

[99] CELLULAR-LEVELS OF PHOTOSENSITIZERS IN TUMORS - THE ROLE OF PROXIMITY TO THE BLOOD-SUPPLY [J].

KORBELIK, M ;

KROSL, G .

BRITISH JOURNAL OF CANCER, 1994, 70 (04) :604-610

[100] DISTRIBUTION OF PHOTOFRIN BETWEEN TUMOR-CELLS AND TUMOR ASSOCIATED MACROPHAGES [J].

KORBELIK, M ;

KROSL, G ;

OLIVE, PL ;

CHAPLIN, DJ .

BRITISH JOURNAL OF CANCER, 1991, 64 (03) :508-512

← 5 6 7 8 9 10 11 12 13 14 →