Functionalised benzo[a]phenoxazine dyes as long-wavelength fluorescent probes for amino acids

被引：57

作者：

Frade, Vania H. J.

Coutinho, Paulo J. G.

Moura, Joao C. V. P.

Goncalves, M. Sameiro T. ^{[1
]}

机构：

[1] Univ Minho, Ctr Quim, P-4710057 Braga, Portugal

[2] Univ Minho, Ctr Fis, P-4710057 Braga, Portugal

来源：

TETRAHEDRON | 2007年 / 63卷 / 07期

关键词：

long-wavelength fluorescent dyes; functionalised probes; benzo[a]phenoxazine; fluorescent labelling; amino acids;

D O I：

10.1016/j.tet.2006.12.005

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of monoreactive functional benzo[a]phenoxazinium chlorides with a carboxyl, hydroxyl, amine or chloromethyl group were used as labels in the preparation of long-wavelength fluorescent amino acid bioconjugates. UV-visible and fluorescence studies of all compounds were carried out in ethanol and water at physiological pH. The absorption and emission of all compounds synthesised were in the range 555-640 nm and 632-681 nm, respectively. (c) 2006 Elsevier Ltd. All rights reserved.

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收藏

页码：1654 / 1663

页数：10

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