Solid-phase extraction and reversed-phase high-performance liquid chromatography of the five major alkaloids in Narcissus confusus

被引：30

作者：

López, S ^{[1
]}

Bastida, J ^{[1
]}

Viladomat, F ^{[1
]}

Codina, C ^{[1
]}

机构：

[1] Univ Barcelona, Fac Pharm, Dept Nat Prod Plant Biol & Edaphol, Barcelona 08028, Spain

来源：

PHYTOCHEMICAL ANALYSIS | 2002年 / 13卷 / 06期

关键词：

high-performance liquid chromatography; solid-phase extraction; alkaloids; galanthamine; amaryllidaceae; Narcissus confusus;

D O I：

10.1002/pca.660

中图分类号：

Q5 [生物化学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

A novel, fast and precise method, combining solid-phase extraction and reversed-phase high-performance liquid chromatography is described for the quantitative determination of five alkaloids (galanthamine, N-formylnorgalanthamine, haemanthamine, homolycorine and tazettine/pretazettine) from bulbs of wild Narcissus confusus, a high galanthamine-containing plant species growing in the Iberian Peninsula. Copyright (C) 2002 John Wiley Sons, Ltd.

引用

收藏

页码：311 / 315

页数：5

相关论文

共 19 条

[1]

Lycorine: A powerful inhibitor of L-galactono-gamma-lactone dehydrogenase activity [J].

Arrigoni, O ;

DeGara, L ;

Paciolla, C ;

Evidente, A ;

dePinto, MC ;

Liso, R .

JOURNAL OF PLANT PHYSIOLOGY, 1997, 150 (03) :362-364

[2]

NARCISSUS ALKALOIDS .4. ALKALOIDS FROM NARCISSUS-CONFUSUS [J].

BASTIDA, J ;

VILADOMAT, F ;

LLABRES, JM ;

CODINA, C ;

FELIZ, M ;

RUBIRALTA, M .

PHYTOCHEMISTRY, 1987, 26 (05) :1519-1524

[3]

Physiological effects of narciclasine from the mucilage of Narcissus tazetta L. bulbs [J].

Bi, YR ;

Yung, KH ;

Wong, YS .

PLANT SCIENCE, 1998, 135 (01) :103-108

[4]

Cytotoxic and antimalarial alkaloids from Brunsvigia littoralis [J].

Campbell, WE ;

Nair, JJ ;

Gammon, DW ;

Bastida, J ;

Codina, C ;

Viladomat, F ;

Smith, PJ ;

Albrecht, CF .

PLANTA MEDICA, 1998, 64 (01) :91-93

[5]

CLAESSENS HA, 1983, J CHROMATOGR, V275, P345, DOI 10.1016/S0378-4347(00)84380-7

[6]

Solid-phase trapping of solutes for further chromatographic or electrophoretic analysis [J].

Fritz, JS ;

Macka, M .

JOURNAL OF CHROMATOGRAPHY A, 2000, 902 (01) :137-166

[7]

FRITZ JS, 1999, ANAL SOLID PHASE EXT

[8]

ANTIVIRAL (RNA) ACTIVITY OF SELECTED AMARYLLIDACEAE ISOQUINOLINE CONSTITUENTS AND SYNTHESIS OF RELATED SUBSTANCES [J].

GABRIELSEN, B ;

MONATH, TP ;

HUGGINS, JW ;

KEFAUVER, DF ;

PETTIT, GR ;

GROSZEK, G ;

HOLLINGSHEAD, M ;

KIRSI, JJ ;

SHANNON, WM ;

SCHUBERT, EM ;

DARE, J ;

UGARKAR, B ;

USSERY, MA ;

PHELAN, MJ .

JOURNAL OF NATURAL PRODUCTS, 1992, 55 (11) :1569-1581

[9]

INFLUENCE OF CHEMICAL-COMPOSITION OF SOILS ON THE GALANTHAMINE CONTENT IN LEUCOJUM-AESTIVUM [J].

GORINOVA, NI ;

ATANASSOV, AI ;

STOJANOV, DV ;

TENCHEVA, J .

JOURNAL OF PLANT NUTRITION, 1993, 16 (09) :1631-1636

[10]

THE PHARMACOLOGY OF GALANTHAMINE AND ITS ANALOGS [J].

HARVEY, AL .

PHARMACOLOGY & THERAPEUTICS, 1995, 68 (01) :113-128