Directed Pd(0)-catalyzed hydrostannations of internal alkynes

被引：16

作者：

Marshall, JA ^{[1
]}

Bourbeau, MP ^{[1
]}

机构：

[1] Univ Virginia, Dept Chem, Charlottesville, VA 22904 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 05期

关键词：

hydrostannation; vinylstannae; poyketide; directing effects;

D O I：

10.1016/S0040-4039(02)02660-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hydrostannations, of primary propargylic alcohols with Bu3SnH catalyzed by Pd(PPh3)(2) yield (E) allylic alcohols in which the Bu3Sn group is affixed to the carbon proximal to the CH2OH substituent, suggestive of an OH directing effect. Hydrostannations of the related propargylic acetates show no such effect. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：1087 / 1089

页数：3

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