Binding of an inhibitor of the p53/MDM2 interaction to MDM2

被引：57

作者：

Duncan, SJ ^{[1
]}

Cooper, MA ^{[1
]}

Williams, DH ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 03期

关键词：

D O I：

10.1039/b211889k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The mode of action of the secondary metabolite chlorofusin, which antagonises the interaction between p53 and MDM2, involves direct binding to the N-terminal domain of MDM2.

引用

页码：316 / 317

页数：2

共 10 条

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