Stretching single stranded DNA, a model polyelectrolyte

被引：176

作者：

Dessinges, MN

Maier, B

Zhang, Y

Peliti, M

Bensimon, D

Croquette, V

机构：

[1] Univ Paris 06, CNRS, Lab Phys Stat, ENS,UMR 8550, F-75231 Paris 05, France

[2] Univ Paris 07, CNRS, Lab Phys Stat, ENS,UMR 8550, F-75231 Paris, France

[3] Columbia Univ, Sherman Fairchild Ctr, New York, NY 10027 USA

[4] D Danforth Plant Sci Ctr, Lab Computat Genom, St Louis, MO 63141 USA

来源：

PHYSICAL REVIEW LETTERS | 2002年 / 89卷 / 24期

关键词：

D O I：

10.1103/PhysRevLett.89.248102

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

The elastic properties of single stranded (ss)DNA, studied by pulling on an isolated molecule, are shown to agree with a recent model of ssDNA that takes into account base pairings and screened electrostatic repulsion of the phosphodiester backbone. By an appropriate physicochemical treatment, the pairing interactions were suppressed and ssDNA used as an experimental model for a generic polyelectrolyte. The elastic behavior of such an altered ssDNA deviates strongly from the behavior of an ideal polymer. This deviation is shown to result from the elasticity of the chain and its electrostatic self-avoiding interactions.

引用

页数：4

共 24 条

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