A highly effective aldol reaction mediated by Ti(O-n-Bu)4/t-BuOK combined reagent

被引：33

作者：

Han, ZF ^{[1
]}

Yorimitsu, H ^{[1
]}

Shinokubo, H ^{[1
]}

Oshima, K ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Sakyo Ku, Kyoto 6068501, Japan

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 22期

基金：

日本学术振兴会;

关键词：

aldol reactions; enals; titanium and compounds;

D O I：

10.1016/S0040-4039(00)00642-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A combined reagent derived from Ti(O-n-Bu)(4) and KO-t-Bu (1:1) has proved to be very effective for the self-aldol addition and also for the cross-aldol condensation between aldehyde and alpha,beta-unsaturated aldehyde such as 2-alkenal or 2-alkynal. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：4415 / 4418

页数：4

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