Use of inactivated bluetongue virus serotype 8 vaccine against virulent challenge in sheep and cattle

被引：31

作者：

Hamers, C. ^{[1
]}

Galleau, S. ^{[1
]}

Chery, R. ^{[1
]}

Blanchet, M. ^{[1
]}

Besancon, L. ^{[2
]}

Cariou, C. ^{[2
]}

Werle-Lapostolle, B. ^{[2
]}

Hudelet, P. ^{[2
]}

Goutebroze, S. ^{[1
]}

机构：

[1] Merial SAS, F-01150 St Vulbas, France

[2] Merial SAS, F-69007 Lyon, France

来源：

VETERINARY RECORD | 2009年 / 165卷 / 13期

关键词：

NORTHERN EUROPE; CULICOIDES; PROTECTION; PARTICLES; EFFICACY; PROTEINS; VECTOR;

D O I：

10.1136/vr.165.13.369

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The immunisation properties of an inactivated bluetongue virus serotype 8 (BTV-8) vaccine were evaluated in sheep and cattle. Five sheep were vaccinated with one dose of vaccine and five cattle were vaccinated with two doses 28 days apart. Six sheep and five cattle served as unvaccinated controls. All animals were subjected to a virulent BTV-8 challenge, and safety and antibody responses were monitored. All control animals developed disease and viraemia, while vaccinated animals were clinically protected and viraemia was completely prevented.

引用

收藏

页码：369 / 373

页数：5

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