Electrospray Ionization Mass Spectrometry of Intrinsically Cationized Nanoparticles, [Au144/146(SC11H22N(CH2CH3)3+)x(S(CH2)5CH3)y]x+

被引：110

作者：

Fields-Zinna, Christina A. ^{[1
]}

Sardar, Rajesh ^{[1
]}

Beasley, Christopher A. ^{[1
]}

Murray, Royce W. ^{[1
]}

机构：

[1] Univ N Carolina, Kenan Labs Chem, Chapel Hill, NC 27599 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 44期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

GOLD CLUSTER MOLECULES; DRUG-DELIVERY; KDA GOLD; MONOLAYER; NANOCLUSTERS; BIOLOGY; ELECTROCHEMISTRY; FRAGMENTATION; COMPOUND; SIZE;

D O I：

10.1021/ja906976w

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Electrospray ionization triple-quadrupole mass spectrometry of ca. 1.6 nm diameter thiolate-protected gold nanoparticles has been achieved at higher resolution than in previous reports. The results reveal the presence of nanoparticles with formulas Au144L60 and Au146L59, present in the sample as a mixture. The improved resolution is based on lowering m/z by exchanging multiple [-SC11H22N(CH2CH3)(3)(+)] ligands into the original [-S(CH2)(5)CH3] ligand shell. The nanoparticles are thus intrinsically cationized and appear as a series of 10+ to 15+ mass spectral peaks. The assigned state of charge was confirmed by a collision-induced dissociation measurement.

引用

页码：16266 / 16271

页数：6

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