Role of acupuncture in the treatment of female infertility

被引:92
作者
Chang, R
Chung, PH
Rosenwaks, Z
机构
[1] Cornell Univ, Weill Med Coll, Ctr Reprod Med & Infirtil, Dept Internal Med, New York, NY 10021 USA
[2] Cornell Univ, Weill Med Coll, Inst E W Med, New York, NY 10021 USA
关键词
acupuncture; female infertility; in vitro fertilization;
D O I
10.1016/S0015-0282(02)04348-0
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To review existing scientific rationale and clinical data in the utilization of acupuncture in the treatment of female infertility. Design: A MEDLINE computer search was performed to identify relevant articles. Result(s): Although the understanding of acupuncture is based on ancient medical theory, studies have suggested that certain effects of acupuncture are mediated through endogenous opioid peptides in the central nervous system, particularly beta-endorphin. Because these neuropeptides influence gonadotropin secretion through their action on GnRH, it is logical to hypothesize that acupuncture may impact on the menstrual cycle through these neuropeptides. Although studies of adequate design, sample size, and appropriate control on the use of acupuncture on ovulation induction are lacking, there is only one prospective randomized controlled study examining the efficacy of acupuncture in patients undergoing IVF. Besides its central effect, the sympathoinhibitory effects of acupuncture may impact on uterine blood flow. Conclusion(s): Although the definitive role of acupuncture in the treatment of female infertility is yet to be established, its potential impact centrally on the hypothalamic-pituitary-ovarian axis and peripherally on the uterus needs to be systemically examined. Prospective randomized controlled studies are needed to evaluate the efficacy of acupuncture in female fertility treatment.
引用
收藏
页码:1149 / 1153
页数:5
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