Choline-containing lipids in mycoplasmas

被引：9

作者：

Rottem, S ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Hadassah Med Sch, Dept Membrane & Ultrastruct Res, IL-91120 Jerusalem, Israel

来源：

MICROBES AND INFECTION | 2002年 / 4卷 / 09期

关键词：

Mycoplasma fermentans; mycoplasma membranes; choline-containing lipids; MfGL-II; ether lipids; membrane fusion; immunomodulin; apoptosis; platelet-activating factor; molt-3; cells; rat astrocytes;

D O I：

10.1016/S1286-4579(02)01622-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Choline-containing lipids were identified and characterized in the cell membrane of Mycoplasma fermentans and were shown to participate in the adhesion to the surface of eukaryotic cells, to stimulate mycoplasma fusion with eukaryotic cells, and to induce cytokine secretion by cells of the immune system. These findings suggest that choline-containing lipids are important mediators of tissue pathology in the infectious process caused by M. fermentans. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

收藏

页码：963 / 968

页数：6

相关论文

共 53 条

[1] THE STRUCTURE OF PNEUMOCOCCAL LIPOTEICHOIC ACID - IMPROVED PREPARATION, CHEMICAL AND MASS-SPECTROMETRIC STUDIES [J].

BEHR, T ;

FISCHER, W ;

PETERKATALINIC, J ;

EGGE, H .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1992, 207 (03) :1063-1075

[2] Choline deficiency induced by Mycoplasma fermentans enhances apoptosis of rat astrocytes [J].

Ben-Menachem, G ;

Mousa, A ;

Brenner, T ;

Pinto, F ;

Zähringer, U ;

Rottem, S .

FEMS MICROBIOLOGY LETTERS, 2001, 201 (02) :157-162

[3] The physico-chemical characteristics of the phosphocholine-containing glycoglycerolipid MfGL-II govern the permeability properties of Mycoplasma fermentans [J].

Ben-Menachem, G ;

Byström, T ;

Rechnitzer, H ;

Rottem, S ;

Rilfors, L ;

Lindblom, G .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 2001, 268 (13) :3694-3701

[4] The phosphocholine motif in membranes of Mycoplasma fermentans strains [J].

Ben-Menachem, G ;

Zähringer, U ;

Rottem, S .

FEMS MICROBIOLOGY LETTERS, 2001, 199 (01) :137-141

[5] Mycoplasma fermentans glycolipid triggers inflammatory response in rat astrocytes [J].

Ben-Menachem, G ;

Rottem, S ;

Tarshis, M ;

Barash, V ;

Brenner, T .

BRAIN RESEARCH, 1998, 803 (1-2) :34-38

[6] Antibody response to MfGL-II phosphocholine-containing major lipid of Mycoplasma fermentans membranes [J].

BenMenachem, G ;

Wagner, F ;

Zahringer, U ;

Rietschel, ET ;

Rottem, S .

FEMS MICROBIOLOGY LETTERS, 1997, 154 (02) :363-369

[7] THE PATHOGENESIS OF SEPSIS [J].

BONE, RC .

ANNALS OF INTERNAL MEDICINE, 1991, 115 (06) :457-469

[8] Interactions between mycoplasma lipoproteins and the host immune system [J].

Chambaud, I ;

Wróblewski, H ;

Blanchard, A .

TRENDS IN MICROBIOLOGY, 1999, 7 (12) :493-499

[9]

Cole B C, 1991, Curr Top Microbiol Immunol, V174, P107

[10]

CULLIS PR, 1988, MOL MECHANISMS MEMBR, P37

← 1 2 3 4 5 6 →