A new coumarin and polyhydroxysqualenes from Ekebergia benguelensis

被引：7

作者：

Jonker, SA

Nkunya, MHH

Mwamtobe, L

Geenevasen, J

Koomen, GJ

机构：

[1] UNIV DAR ES SALAAM,DEPT CHEM,DAR ES SALAAM,TANZANIA

[2] UNIV AMSTERDAM,ORGAN CHEM LAB,NL-1018 WS AMSTERDAM,NETHERLANDS

来源：

NATURAL PRODUCT LETTERS | 1997年 / 10卷 / 04期

关键词：

Ekebergia benguelensis; Meliaceae; 4-methoxy-5-hydroxymethylcoumarin; 2,3,22,23-tetrahydroxy-2,6,10,15,19,23-hexamethyl-6,10,14,18-tetracosatetraene; 2-hydroxymethyl-2,3,22,23-tetrahydroxy-6,10,15,19,23-pentamethyl-6,10,14,18-tetracosatetraene;

D O I：

10.1080/10575639708043736

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new coumarin, 4-methoxy-5-hydroxymethylcoumarin was isolated from the root bark of Ekebergia benguelensis, together with the polyhydroxysqualenes, 2,3,22,23-tetrahydroxy-2,6,10,15,19,23-hexamethyl-6,10,14,18-tetracosatetraene and 2-hydroxymethyl-2,3,22,23-tetrahydroxyl-6,10,15,19,23-pentamethyl-6,10,14,18-tetracosatetraene, besides a mixture of 3 alpha-hydroxy-12-oleanen-28-oic and 3-oxo-12-oleanen-28-oic acids. Structural determination was achieved by spectroscopic analyses.

引用

页码：245 / 248

页数：4

共 8 条

[1] 2,3/18,19-DIOXIDOSQUALENE - SYNTHESIS AND ACTIVITY AS A POTENT INHIBITOR OF 2,3-OXIDOSQUALENE-LANOSTEROL CYCLASE IN RAT-LIVER MICROSOMES [J].