Analysis of illicit drugs by nonaqueous capillary electrophoresis and electrochemical detection

被引：36

作者：

Backofen, U

Matysik, FM

Hoffmann, W

Lunte, CE ^{[1
]}

机构：

[1] Univ Kansas, Dept Chem, Lawrence, KS 66045 USA

[2] Univ Leipzig, Inst Analyt Chem, D-04103 Leipzig, Germany

[3] Forschungszentrum Karlsruhe, Inst Instrumentelle Analyt, D-76344 Eggenstein Leopoldshafen, Germany

来源：

FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY | 2000年 / 367卷 / 04期

关键词：

D O I：

10.1007/s002160000371

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Nonaqueous capillary electrophoresis (NACE) was applied to the determination of illicit drugs. The complete separation of amphetamine, methamphetamine, 3,4-methylene dioxy amphetamine (MDA), 3,4-methylene dioxy methamphetamine (MDMA), mescaline, cocaine and benzoylecgonine was obtained using an acetonitrile based buffer solution containing 10 mM sodium acetate and 1 M acetic acid. Electrochemical detection using a Pt microdisk electrode set to a potential of + 1.8 V was found to be selective for MDA, MDMA and mescaline. The detection limits for these compounds were in the low ng/mL range which is between 2 and 3 orders of magnitude lower compared to UV-detection.

引用

页码：359 / 363

页数：5

共 31 条

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