Hypertension in the Elderly

被引:33
作者
Acelajado, Maria Czarina [1 ]
Oparil, Suzanne [1 ]
机构
[1] Univ Alabama Birmingham, Vasc Biol & Hypertens Program, Div Cardiovasc Dis, Dept Med,Sch Med, Birmingham, AL 35294 USA
关键词
Elderly; Hypertension; Pathophysiology; Diagnosis; Management; ISOLATED SYSTOLIC HYPERTENSION; AMBULATORY BLOOD-PRESSURE; LIPID-LOWERING TREATMENT; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; CALCIUM-CHANNEL BLOCKER; DOUBLE-BLIND; ORTHOSTATIC HYPOTENSION; CARDIOVASCULAR-DISEASE; ARTERIAL STIFFNESS; COGNITIVE FUNCTION;
D O I
10.1016/j.cger.2009.06.001
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
030301 [社会学]; 100201 [内科学];
摘要
Hypertension is an important risk factor for cardiovascular morbidity and mortality, particularly in the elderly. Blood pressure elevation in the elderly is due to structural and functional changes that occur with aging. Treatment of hypertension reduces the risk of stroke, heart failure, myocardial infarction, all-cause mortality, cognitive impairment, and dementia in elderly patients with hypertension. A healthy lifestyle helps hypertension management, with benefits extending beyond lowering of blood pressure. Several classes of anti hypertensive drugs are effective in preventing cardiovascular events. Treatment decisions should be guided by the presence of compelling indications such as diabetes or heart failure and by the tolerability of individual drugs or drug combinations in individual patients. The concomitant intake of certain medications that counter the effects of antihypertensive drugs and the frequent occurrence of orthostatic hypotension complicate treatment in older patients and drive down blood pressure control rates.
引用
收藏
页码:391 / +
页数:23
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