The human and mouse MHC class III region: a parade of 21 genes at the centromeric segment

被引：37

作者：

Yu, CY ^{[1
]}

Yang, ZY

Blanchong, CA

Miller, W

机构：

[1] Ohio State Univ, Childrens Res Inst, Div Hematol Oncol, Columbus, OH 43205 USA

[2] Ohio State Univ, Col Med & Publ Hlth, Columbus, OH 43205 USA

[3] Penn State Univ, Dept Comp Sci & Engn, University Pk, PA 16802 USA

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 07期

关键词：

D O I：

10.1016/S0167-5699(00)01664-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The human major histocompatibility complex (MHC) class III region contains 57-60 structural genes spanning 654-759 kb of genomic DNA. Analysis of the sequence identities of the human and mouse genomic regions between NOTCH4 and complement C2 yields important information on the locations of the coding and regulatory sequences. I also provides insights into the relationship between protein function and level of sequence conservation, and on the clustering of genes with related functions.

引用

页码：320 / 328

页数：9

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