Mapping of 59 EST gene markers in 31 intervals spanning the human X chromosome

被引：10

作者：

Gianfrancesco, F

Esposito, T

Ruini, L

Houlgatte, R

Nagaraja, R

DEsposito, M

Rocchi, M

Auffray, C

Schlessinger, D

DUrso, M

Forabosco, A

机构：

[1] CNR,INT INST GENET & BIOPHYS,I-80125 NAPLES,ITALY

[2] UNIV MODENA,DIPARTIMENTO SCI MORFOL & MEDICOLEGALI,SEZ ISTOL EMBRIOL & GENET,I-41100 MODENA,ITALY

[3] CNRS,UPR 420,F-94801 VILLEJUIF,FRANCE

[4] WASHINGTON UNIV,SCH MED,DEPT MOL MICROBIOL,ST LOUIS,MO 63110

[5] IST GENET,I-70126 BARI,ITALY

来源：

GENE | 1997年 / 187卷 / 02期

关键词：

human genome; somatic cell hybrid; X physical and genetic map; X-linked disease;

D O I：

10.1016/S0378-1119(96)00743-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The positioning of Expressed Sequence Tags (ESTs) constitutes an important step towards a functional map of the human genome, including candidate genes for human genetic disorders that have been localized by linkage analysis. We localized 59 ESTs on the human X chromosome, including 44 derived from infant brain and 15 from adult muscle cDNA libraries. Localizations by a somatic cell hybrid panel were refined for five cDNAs by mapping them in yeast artificial chromosome (YAC) contigs.

引用

页码：179 / 184

页数：6

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