A convenient synthesis of monpain trimethylether.

被引：9

作者：

Bekaert, A

Andrieux, J

Plat, M

Brion, JD

机构：

[1] Lab. de Chimie Thérapeutique, Fac. de Pharm. Univ. de Paris XI, Associé au CNRS BIOCIS, F 92290 Châtenay-Malabry, rue Jean-Baptiste Clément

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 24期

关键词：

D O I：

10.1016/S0040-4039(97)00860-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A high yield synthesis of various 2-hydroxy-1,4-naphtoquinones was achieved by SeO2 oxidation of 1-tetralones into the corresponding 1,2-quinones, followed by heterogeneous phase KO2 mediated oxidation. Application of this synthesis to 5,7,8-trimethoxy-1-tetralone gave 2-hydroxy-5,7,8-trimethoxy-1,4-naphtoquinone 3d or monpain trimethylether. (C) 1997 Elsevier Science Ltd.

引用

页码：4219 / 4220

页数：2

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