Molecular determinants of presynaptic active zones

被引:156
作者
Garner, CC [1 ]
Kindler, S
Gundelfinger, ED
机构
[1] Univ Alabama Birmingham, Dept Neurobiol, Birmingham, AL 35294 USA
[2] Univ Hamburg, Inst Cellular Biochem & Clin Neurobiol, D-20246 Hamburg, Germany
[3] Leibniz Inst Neurobiol, D-39118 Magdeburg, Germany
关键词
D O I
10.1016/S0959-4388(00)00093-3
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The presynaptic cytoskeletal matrix (cytomatrix) assembled at active zones has been implicated in defining neurotransmitter release sites. Munc13, Rim, Bassoon and Piccolo/Aczonin are recently identified presynaptic cytomatrix proteins. These multidomain proteins are thought to organize the exocytotic and endocytotic machinery precisely at active zones.
引用
收藏
页码:321 / 327
页数:7
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