Polar body formation: new rules for asymmetric divisions

被引：109

作者：

Maro, B ^{[1
]}

Verlhac, MH ^{[1
]}

机构：

[1] Univ Paris 06, UMR 7622, CNRS, F-75005 Paris, France

来源：

NATURE CELL BIOLOGY | 2002年 / 4卷 / 12期

关键词：

D O I：

10.1038/ncb1202-e281

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Asymmetric cell divisions are pivotal throughout development and generate cell diversification within the embryo. The formation of polar bodies during oocyte meiotic maturation provides the most extreme case of size difference between two daughter cells. New work in this issue indicates that formin-2, a microfilament-binding protein, is required for the eccentric positioning of the meiotic spindle that determines these unequal divisions.

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收藏

页码：E281 / E283

页数：4

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